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(You may also see the term metabolic dysfunction-associated steatotic liver disease, or MASLD, used in newer literature, though NICE guidance currently refers to NAFLD.) Additionally, NAC possesses direct antioxidant properties and may help modulate inflammatory pathways within the liver

The ratio between these forms serves as an important indicator of cellular oxidative stress

In conclusion, our data suggest that GSSG is a potent and clinically relevant sensitizer for TNF-induced hepatotoxicity in NAFLD, which represents a potential therapeutic target for NAFLD

While NAC differs from NAD+, it supports cellular energy indirectly by boosting glutathione production