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GLP-1

In the STEP trials, semaglutide 2.4 mg weekly showed average weight reductions of 1215% of body weight over 68 weeks, whilst in the SCALE trials, liraglutide 3 mg daily typically produced 58% weight loss

Bianca Itariu: declares no conflict of interest relevant to this study

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Type 1 diabetes By exploiting GLP-1s glucose-dependent glucagonostatic effect and its inhibiting effect on gastric emptying, treatment with GLP-1RAs could supplement insulin treatment in patients with type 1 diabetes (T1D)

Dosages can be increased every 30 days until the maximum dose is reached