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The American College of Physicians guidelines note that continued treatment is necessary to maintain weight loss, as discontinuation often leads to weight regain

However, they generally do not cover Ozempic when prescribed off-label for weight loss in patients without diabetes

But if you show a flat response to tirzepatide as well, that is worth a direct conversation with your provider about whether GLP-1 therapy is the right primary approach for you

Phase 4: Maintenance optimization (weeks 25 onward) This is where individual adjustment matters most

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Common adverse effects include nausea, vomiting, diarrhoea, and constipation, which are usually transient and improve with dose titration