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In most cases, the condition is self-limited and responds to supportive care and symptomatic relief including rest, elevation if a dependent extremity is affected, and use of compression stockings

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After 15 min, 0.1% DMSO or 8.4 M HC were added in each well and the fluorescence intensity of the dye was measured for additional 15 min

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SQOR deficiency causes H 2 S to accumulate and potently inhibit cytochrome c oxidase (Complex IV), resulting in a state of tissue hypoxia and metabolic crisis in the brain