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Direct innervation of the PB by neurons originating in the NTS and AP in the brainstem and in the hypothalamic ARH have been demonstrated (88, 89), suggesting an activation pathway for endogenous blood-borne hormones, such as leptin (27), ghrelin (90), and GLP-1 (8), that affects PB signaling
[26] Terns Pharmaceuticals
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Dosing errors can also lead to more severe side effects, which can last up to a few weeks, as semaglutide stays in the body for a long time
