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Gastrointestinal side effects are the most frequently reported adverse reactions to GLP-1 receptor agonists, affecting a significant proportion of patients, particularly during initial treatment or dose escalation

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5) Sleep Deprivation Sleep deprivation increased TMAO levels in 15 healthy men [53]

Other medications Some drugs interact with semaglutide and may cause mood-related side effects

Quality and dosage of berberine can vary significantly between products, as dietary supplements are not subject to the same stringent manufacturing standards as prescription medicines