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LSECs have multiple functions such as anti-inflammatory, endocytic clearance, sinusoidal capillarization, and secretion of pro-angiogenic signaling factors

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Ultimately though, the antifibrotic effects conferred by compounds derived from TCM target critical signaling nodes such as TGF-/Smad which play pivotal roles in EMT and ECM synthesis (Na et al., 2018) (Figures 2, 3)

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In a separate study, an improved in vitro skin permeation of testosterone was observed when utilizing ethosomes, a result that is consistent with our findings