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TMAO (trimethylamine N-oxide) is produced by gut bacteria from choline, lecithin, and L-carnitine-rich foods (mainly fish, meat, egg, and dairy)

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Hence, ferroptosis is likely not a major contributing factor in APAP-induced hepatotoxicity under physiological conditions

35,36 Following the identification of microbiome changes, we conducted a striatal metabolomics analysis and observed TS-induced abnormalities in striatal metabolism in rats

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