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Third, the establishment of definite causal relationship between a target drug and AEs is restricted because disproportionality analysis only provides statistical association

The mean BMI was 38.5 (7.7) kg/m 2 for the CeD+AOM group and 37.7 (8.0) kg/m 2 for the AOM group

Availability of data and materials The data that support the findings of this study are available from Centers for Medicare & Medicaid Services (CMS), but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available