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It is used in addition to diet and exercise for long-term weight management in adults with obesity, or adults overweight with at least one weight-related medical problem (for example: hypertension, high cholesterol, type 2 diabetes, obstructive sleep apnea or heart disease)

This damage can cause trouble with memory, irritability, and other cognitive impairments in the elderly

44 Together, impaired insulin and IGF1 signalling establish a chronic metabolicinflammatory milieu that disrupts neuronal energy metabolism and redox homeostasis

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