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These similarities with our model carrying TrKB depletion in iSPNs suggest a new concept for BDNFTrkB signalling in the context of striatal protection modulating dopamine circuits through metabolic pathways such as glutathioneascorbate and energy metabolism

Tirzepatide slows gastric emptying, which means large meals, high-fat foods, and heavy meals can cause significant nausea and discomfort

Another example is that of the cone snail, whose venom has yielded a chronic painkiller

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It is characterized by irregular menstrual cycles, endocrine changes, and often has accompanying symptoms such as hot flashes

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