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Association between vascular endothelial growth factor and clinical outcomes of IVF-ET/ICSI

While most clinical evidence supports a favorable safety profile at typical therapeutic doses, caution is warranted as higher doses may cause sedation, cardiovascular effects such as hypotension and arrhythmias, and, in rare cases, respiratory depression

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Fine lines may appear less pronounced, though this is primarily due to improved hydration rather than structural changes

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