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SGLT2GLP-1 20234 GIP/GLP-1 GIP/GLP11 GLP-1 GLP-1GIPGIP/GLP-1 GLP-1 GLP-1-1GLP-1 GLP-1GLP-1 GIP GIPGLP-1 GIP GLP-1GIP HbA1c SRPUSS J-mono2 HbA15mg/10mg/15mg10.75 2636 HbA1c 5mg-2.4 10mg-2.6 15mg-2.8 0.75mg-1.3 HbA1c 52HbA1c7.0 5mg94% 10mg97% 15mg99% 0.75mg67% 9HbA1c7.0 5mg-5.8kg 10mg-8.5kg 15mg-10.7kg 0.75mg-0.5kg 15mg-10.7kg 16~18% 12~20%14~18%13~22%9~17%5~12% 8%11%4%11%1% HbA1c 1 0.25mg40.5mg 40.25mg 2.5mg1924/ 5mg3848/ 7.5mg5772/ 10mg7696/ 15mg11544/ 2807/ 2mg11008/ 432300~14000 2 Kadowaki T, Chin R, Ozeki A, et al
Even as the clinical community works to establish the long-term benefits of current GLP-1 and HRT combinations, a new generation of metabolic therapies is already moving through trials, ones that extend the biological logic of this article's central argument into territory that semaglutide and tirzepatide alone cannot reach