Lancet, 2021
reported that among 18,507 participants with no history of hospitalization due to heart disease or stroke and who were known not to be pregnant, the median GDF15 level was 816 pg/mL in women and 793 pg/mL in men
The peptide is derived from a partial sequence of a larger protein found in human gastric juice called BPC, which was first isolated and characterized in the early 1990s
In ATTAIN-1, 3,127 overweight participants without diabetes were enrolled, while in ATTAIN-2, 1,613 overweight patients with type 2 diabetes were enrolled
We generated two BWS-iPSC lines from a parental control line using a CRISPR-Cas9 approach
Regardless of whether the GGT level was above the upper normal limit or not, the effect size increased significantly as the GGT level rose