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Standard reconstitution uses bacteriostatic water, which contains a preservative allowing the solution to remain stable for weeks when refrigerated

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The increased risk of thrombosis and heart attack observed in some studies of COX-2 inhibitors may result from this mechanism (Conaghan 2012)

[DOI] [PMC free article] [PubMed] [Google Scholar] 156.Sachs S., Bastidas-Ponce A., Tritschler S., Bakhti M., Bttcher A., Snchez-Garrido M.A., Tarquis-Medina M., Kleinert M., Fischer K., Jall S., et al

There is also minimal pain, redness and swelling post-treatment