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This slowdown in muscle activity can sometimes lead to complications such as gastroparesis, where food may either solidify or necessitate vomiting after prolonged stomach retention

Methods Using data from the EQ-DAPHNIE project, 5403 respondents aged 65 years or older were included from Canada (n=1312), United States (US) (n=1069), United Kingdom (UK) (n=970), Australia (n=1224), and New Zealand (n=828), with analyses conducted overall and by age groups (65-69, 70-74, 75-79, 80) for each country

In addition, the forced and intensive dose escalation with large increments may have impacted potential risk-benefit effects