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Possible changes in plasma levels of hepatically metabolized drugs Need for monitoring when used with narrow therapeutic index agents Concomitant administration with antioxidants and vitamin supplements is generally well tolerated, though excessive antioxidant load may blunt physiological redox signaling

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Approximately 33% of patients had two or more tests during this time period

[DOI] [PubMed] [Google Scholar] Garca Muoz R, Izquierdo-Gil A, Muoz A, Roldan-Galiacho V, Rabasa P, Panizo C, 2014