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In mouse models of colitis (DSS- and TNBS-induced), orally delivered KPV decreased pro-inflammatory cytokine expression and attenuated disease severity

255 It is worth noting that in DCs treated with zinc chloride (ZnCl 2 ), MT1 insufficiency fails to promote a regulatory phenotype specifically aimed at modulating T cell behavior or stimulate the proliferation, such as active growth, of FoxP3 + T cells

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While the region is known mostly for vision, it may also help process emotions and sensory experiences

doi: 10.1007/s40257-014-0107-3