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For a long time, they were primarily considered harmful due to their potential for causing damage

Various compounds, including tanshinone IIA, have demonstrated cardioprotective effects by activating Nrf2 and its downstream antioxidant genes [80]

In the volcano plot, microbiome-derived propionate emerged as the metabolite with the most statistically significant decrease, while BHB derived from liver stood out as the most significantly increased metabolite (Fig

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(2023) describe food-related intrusive thoughts (FRITs) as what happens when food cues - whether internal, like feeling a bit hungry, or external, like seeing a fast-food sign - trigger the DMN into a craving loop [6]