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In a large clinical trial (again in people with obesity or overweight, but not necessarily PCOS), participants lost 2% of their body weight within the very first month

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Int J Devl Neurosci 47:259265 Derks TGJ, Touw CML, Ribas GS et al (2014) Experimental evidence for protein oxidative damage and altered antioxidant defense in patients with medium-chain acyl-CoA dehydrogenase deficiency