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However, in rare cases, Ozempic can also lead to more serious GI problems, such as: It is essential for individuals taking Ozempic to be aware of these potential risks and to consult their healthcare provider if they experience any unusual symptoms

My advice is to take the lowest effective dose

Krieger T, Zimmermann J, Huffziger S et al (2014) Measuring depression with a well-being index: further evidence for the validity of the WHO Well-Being Index (WHO-5) as a measure of the severity of depression

2013 May;21(5):303-11

Last updated on Apr 1, 2026

Backup contraception may be recommended for 4 weeks after starting tirzepatide and for 4 weeks after each dose increase