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When tumors were increased to 100 mm 3 in volume, 100 L of DOX, or DOX/LAAM GSH-CQDs at a dose equivalent to 5 mg kg 1 DOX was injected into the mice veins ( n = 3)

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Therefore, a better understanding of the mechanisms regulating endothelial cell manipulation in cancer may improve the efficacy and success of current immunotherapeutic approaches