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Furthermore, evidence indicates that NRF2 can transcriptionally upregulate CHAC1, as observed in ferroptosis-resistant melanoma cells where CHAC1 induction occurs independently of ER stress ( de novo GSH synthesis (Kre et al., 2023)
Every experiment was repeated at least three times, and representative data are shown
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Extreme elevation of serum growth hormone-binding protein concentrations resulting from a novel heterozygous splice site mutation of the growth hormone receptor gene