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The condition involves the painful thinning of fat pads on the soles of the feet due to rapid weight loss, leaving users with a raw, bruised feeling when walking

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For quality assurance and quality control, molecular negative template controls (NTC) consisting of PCR-grade water (Invitrogen, Waltham, MA, USA) along with positive controls created by linearized plasmids were run on every qPCR plate

It does this by a few different mechanisms that all help to reduce the number of melanin-containing cells in the skin