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However, it is important to note that overall metabolism of tryptophan includes not just its catabolism but also its use in the synthesis of serotonin and melatonin, the synthesis of indole derivatives such as the trace amine, tryptamine, and the synthesis of NAD +

doi: 10.3748/wjg.v13.i35.4707 178 PramanikA.StroeherU

Further, the peptide has also been found to exert antioxidant effects, while inhibiting carcinogenic receptor expression, giving it anti-tumor effects in breast and colorectal cancer [5, 6]

Additionally, Pink1 may be involved in the regulation of mitochondrial fission and fusion homeostasis independently of mitophagy

The expression levels for each of the genes were normalized to fragments per kilobase of exon model per million mapped reads (FPKM) using a software package called RSEM 79

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