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When supplementing, it's important to note that the Tolerable Upper Intake Level (UL) from supplements is 350 mg per day for adults

Injection-site and systemic risks : Improper reconstitution or non-sterile technique can introduce bacteria or particulates into the solution, leading to localised infections, abscesses, or, in severe cases, systemic sepsis

If you take any diuretic, your healthcare provider should be monitoring electrolyte levels closely and may recommend specific supplementation protocols

Phase 3 trials are urgently needed to clarify efficacy and safety of retatrutide

Use with liquids below 140F for best results

New England Journal of Medicine , 389(6), 514526