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Ding X, Wang T, Shen Y, Wang X, Zhou C, Tian S, et al

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The hypoglycaemia risk arises because IGF-1R cross-activates the insulin receptor at supraphysiologic concentrations, stimulating GLUT4 translocation and glucose uptake [3]

To facilitate inter-mice statistics, each rs-fMRI image was spatially smoothed (0.5 mm isotropic Gaussian kernel), and each voxels time series was bandpass filtered from 0.01 to 0.3 Hz [40, 41]