Our analyses displayed that endometriosis could be polyepigenetic and with alterations in specific genes implicated in major signaling pathways contributing to the disease etiopathology (cell proliferation, differentiation, and division [PI3K-Akt and Wnt-signaling pathway], cell division [MAPK pathway], cell adhesion, cell communication, developmental processes, response to hormone, apoptosis, immunity, neurogenesis, and cancer)
doi: 10.1038/ncomms3905
Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection
UK Prospective Diabetes Study (UKPDS) Group
These impairments elevate ROS levels, initiating a senescence program that forms a self-reinforcing positive feedback loop
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