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Cardiopulmonary bypass (CPB) is related to multiple effects that may contribute to post-operative myocardial injury and cardiac dysfunction, including ischemiareperfusion injury after removal of the aortic clamp, the subsequent generation of reactive oxygen species, and increased production of inflammatory mediators [2, 3]

The hot plate was maintained at the temperature of 55C, and experimental protocol as previously described (1, 26)

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TB-500 stimulates cell migration through actin-binding, promoting regrowth and repair of injured or inflamed tissues

Sci., 58 : 1007-1010

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