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Results Targeted nanoformulations of both drugs showed elevated cellular uptake in a time-dependent, active manner via endocytic mechanisms

The Zr released from Mn-MOF downregulated GSH efficiently (Figure 5G), thus elevating Mn-MOF-induced ROS concentration, leading to the deactivation of GPX4 and ROS-enhanced ferroptosis

it is a comprehensive medical intervention that pairs the latest in metabolic science with ongoing clinical support, ensuring that patients lose weight safely while addressing the root causes of their metabolic dysfunction

Likewise, PA restored cadmium-induced Nrf2 inhibition to prevent autophagy inhibition and NLRP3 inflammasome activation, providing novel insights into the protection of PA against cadmium-induced hepatic cell damage (Yu et al., 2021)

In this study, they applied antimicrobial peptide SKACP003 against -catenin in three breast cancer cell lines: MCF-7, MDA-MB-453, and MDA-MB-231

Accessed 9 Nov 2025