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Finally, we validated that the peptide inhibitor exhibited robust selectivity for senescent cells and efficiently disrupted FOXO4-p53 foci formation despite its short length and L-type amino acid composition

The sequence of free roGFP2-iL and GRX1-roGFP2-iL were cloned into the BamHI and NcoI restriction sites of the protein expression vector pQE-30 (Qiagen, www.qiagen.com) for the production of a recombinant protein containing an N-terminal His 6 -tag

PMID: 25216859

The pore size of cell culture inserts is an important parameter and we compared cell culture inserts with 3 m and 0.4 m pore sizes (Corning Costar

DNA damage accumulates over time