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Reported sexual-arousal effects are linked to Melanotan 2, which targets additional melanocortin receptors

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Serious adverse events remain rare, particularly when patients receive ongoing medical supervision and dose optimization

Heres what actually matters: The critical distinction: Retatrutide isnt just a little better. The most recent Phase 3 data (TRIUMPH-4 trial, December 2025) showed participants on the 12 mg dose lost an average of 28.7% of their body weight at 68 weeks