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It is, however, important to acknowledge the other side of the coin: the GLP-1 RAs are associated with rapidly increasing expenditures [15], the use of falsified drugs [16, 17], and adverse events such as gastrointestinal adverse events which may be investigated more in the future along with the increased use of the GLP-1 RAs [18, 19]

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Your injection technique might also need adjustment if you experience these issues frequently

The incretins: a link between nutrients and well-being

Overall, the newer small molecule GLP-1 RAs such as danuglipron and orforglipron have shown significant reductions in HbA1c and body weight, comparable to existing GLP-1 RAs

Supplement considerations Certain supplements may support GLP-1 therapy outcomes