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These experiences vary considerably and may also be influenced by lifestyle changes occurring alongside treatment

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For example, considering HepG2, Huh7, and Hep3B, even though they are all epithelial liver cancer cells with high expression of HNF4, HepG2 cells have normal expression of wild-type p53, Huh7 cells overexpress a mutant p53, while Hep3B cells are p53 null 65

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While gabapentin is not known to cause direct kidney damage, impaired kidney function can increase drug levels and side effects