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Both glucose and sodium ions bind to the cotransport protein, with the Na + electrochemical gradient, maintained by the basolateral sodiumpotassium adenosine triphosphatase, driving glucose uptake across the luminal membrane ( Figure 1 )

Potential side effects in subjects may include abnormal growth like acromegaly, water retention, hypoglycemia, nerve, joint, or muscle pain, and heart enlargement

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Furthermore, the functions of other B-vitamin coenzymes, such as vitamin B 6 and folate, are dependent on the actions of flavoproteins