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For some, these transformations occur rapidly, while others experience a more gradual advance over a few months

Polysaccharide from Aloe vera gel improves intestinal stem cells dysfunction to alleviate intestinal barrier damage via 5-HT

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J Clin Med 2019

These barriers are physically represented by the so-called tight junctions between brain endothelial cells and epithelial cells, attributed to the special proteins such as occludin, claudins, and the associated proteins zona occludens (ZO-1, ZO-2, and ZO-3), which are highly expressed in brain endothelium (Chen et al., 2009