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Slow and gradual dose adjustments are key for this group, as they help reduce the risk of gastrointestinal side effects like nausea and vomiting, which could lead to volume depletion

The inflammatory milieu subsequently drives hepatic stellate cell activation and transdifferentiation into myofibroblasts, leading to excessive extracellular matrix deposition and progressive fibrosis, which represents the primary determinant of long-term liver-related outcomes [17]

doi: 10.1089/jop.2025.0025 400 ZhaoLDongXGuoBSongJBiH

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