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Exposure to excess haem-iron was only found to promote a persistent phenotype in experimental OM models for NTHi strains previously starved of haem-iron, compared to those continuously exposed to haem-replete conditions (Szelestey et al., 2013

Signs to stop earlier If you develop persistent gastrointestinal symptoms, body odor that causes social or personal distress, or have a kidney problem that changes labs, stop and seek medical advice

Treatment decisions are based on a medical evaluation, health history, and clinical criteria

Healthcare providers should monitor patients for changes in hormone levels and clinical symptoms, adjusting HRT dosages as needed

104 With respect to the former, selenium is an important trace mineral in the human diet that modulates the peripheral conversion of T4-to-T3 by controlling iodothyronine deiodinase activity