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accordingly, when a supramaximal dose (1 M) of exendin-4 (to fully activate remaining surface receptors) was added in addition to IBMX after prior incubation with each test agonist, a linear relationship between internalization and cAMP response was restored (Fig

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doi: 10.1038/s41598-017-06484-6 225 QuanC.LiC.MaH.LiY.ZhangH

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