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Unlike standard hydration or vitamin IVs that can be delivered in under an hour, NAD+ must be administered at a controlled pace to reduce side effects such as flushing, chest tightness, nausea, or headache

Apparently, its like a banned substance or whatnot

Liu, H., Wang, J., He, T., Becker, S., Zhang, G., Li, D., & Ma, X

doi: 10.14309/00000434-201610001-00591 90 SehgalPSuSZechJNobelYLukLEconomouIet al

Copper interacts with zinc, iron, ceruloplasmin, inflammation, and oxidative stress

As a co-factor in carboxylase enzymes, Biotin is involved in gluconeogenesis, fatty acid synthesis, and the metabolism of amino acids