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We have seen similar effects of GLP1 receptor antagonists in VSG-treated rats, with increases in the glucose nadir 132

This is thought to be related to GLP-1s effects on the brains dopamine reward pathway, says Nitya Kumar, MD, an endocrinologist and an assistant professor of medicine at the Duke University School of Medicine in Durham, North Carolina

On Mounjaro (tirzepatide for type 2 diabetes)

When to seek urgent medical attention: Severe or persistent abdominal pain , especially if accompanied by vomiting, fever, or pain radiating to the back this may indicate pancreatitis

A healthcare provider or Registered Dietitian can help you adjust your plan accordingly

This matters for the cost landscape because small-molecule drugs are inherently less expensive to produce at scale than biologic peptides