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In cuprizone-rats, BPC 157 was given per-orally in the same regimen that may rescue rats with severe ulcerative colitis and colon-colon anastomosis

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In the advancement of treatment strategies, although approaches like mitochondria-targeted antioxidants (e.g., MitoQ) and macrophage metabolic reprogramming (e.g., SDH inhibitors) have shown significant efficacy in animal models, their clinical translation faces severe challenges in targeted delivery and microenvironment adaptation

Niu L-G, Sun N, Liu K-L, Su Q, Qi J, Fu L-Y, et al

Current Heart Failure Reports, 17(2), 108114