Commercial GLP-1 patches dont contain actual GLP-1 medications and cant deliver the same effects
Two studies investigated animal models of comorbid depression and epilepsy 159,161 : one showed that exendin-4 led to an increase in frequency of absence seizures as well as depressogenic and anxiogenic responses 159 , while the other saw a decrease of depression-like behavior for liraglutide irrespective of concurrent use of the antiepileptic levetiracetam 161
Missing doses or varying the time by several hours each day creates peaks and valleys in blood concentration that reduce overall effectiveness and can worsen side effects like nausea
Conversely, data from clinical trials have showed an increased risk of incident heart failure with DPP4 inhibitors compared to placebo
To understand the treatment options in more detail and how they compare in real-world use, you can also read Medical Weight Loss Explained: The Truth About Semaglutide & Liraglutide on Medical Weight Loss Explained: The Truth About Semaglutide & Liraglutide
Eating too quickly or consuming large portions can overwhelm the early fullness produced by GLP-1 medications or increase the risk of side effects
