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Importantly, interindividual variability, including gender differences, hormonal patterns, BC, and microbiota profile, should guide dietary and pharmacological choices

"Lilly's phase 2 retatrutide results published in The New England Journal of Medicine show the investigational molecule achieved up to 17.5% mean weight reduction at 24 weeks in adults with obesity and overweight"

doi: 10.1136/annrheumdis-2015-208442 172 MateenSMoinSShahzadSKhanAQ

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To date, no effective medical interventions exist that completely reverse the disease other than lifestyle changes, dietary alterations and, possibly, bariatric surgery