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[1] [2] Semaglutide's activation of these receptors can influence the chemoreceptor trigger zone, potentially leading to nausea and vomiting independent of gastric effects

2016 Nov;5(11):3353-3367

H., Aalbers, M

Rare but serious adverse effects require vigilance: Acute pancreatitis presents with severe, persistent abdominal pain, often radiating to the back, accompanied by nausea and vomiting

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Today, there are three FDA-approved medications containing GLP-1s as the active ingredient for type 2 diabetes and injections for weight management