The pharmacokinetic groundwork that is also missing Even before an efficacy trial, injectable GHK-Cu lacks the basic human pharmacokinetic characterization that any injectable drug candidate would require: measured plasma half-life of the intact complex, the fraction of administered copper that binds to plasma proteins versus remains peptide-bound, tissue distribution, and how much functional complex if any actually reaches the dermis
To date, TRFS-green has been successfully commercialized and is now used by researchers in various scientific investigations 71,72,73,74,75,76,77,78,79,80,81,82,83
Injectable formulations require prescriber oversight
It could be that, when the drug causes a quick drop in blood sugar, the resulting chemistry change causes blood vessels to the optic nerve to be cut off
2 Getting rid of these cells helps create a healthier internal environment, supporting cellular health and tissue regeneration
Ref cell hydrolases: glycosidase activities in human erythrocyte plasma membranes