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In PsA, insulin resistance has been associated with higher disease activity, greater pain burden, and reduced therapeutic responsiveness, reinforcing the rationale for metabolic interventions as part of a disease-modifying strategy (29)

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doi: 10.1111/j.1464-5491.2012.03771.x 20 Van der SchuerenBEllisDFaradjiRNAl-OzairiERosenJMathieuC