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finally, combining molecular docking techniques to validate the binding modes of drugs and targets, and further evaluating the efficacy and safety of drugs via in vitro cell experiments and in vivo animal experiments (Gogoi and Saikia, 2022

Heer CD, Sanderson DJ, Voth LS, Alhammad YMO, Schmidt MS, Trammell SAJ, et al

Through chemical processes in the body, SAM-e is converted into glutathione, which is known to have detoxifying and antioxidant effects on the liver

Stone et al., 2019), cell aggregate-based models (Urich et al., 2013

Schnrich G, Kalinke U, Momburg F, Malissen M, Schmitt-Verhulst AM, Malissen B, Hmmerling GJ, & Arnold B (1991) Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction