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PA treatment elevated the expression of genes associated with cholesterol synthesis, such as acyl-CoA C-acyltransferase 1 gene ( ACAT1 ), SREBP-2 , HMGCR , and squalene monooxygenase gene ( SQLE ), as well as genes related to bile acid synthesis, including liver X receptor gene ( LXR ) and cholesterol 7-alpha-hydroxylase gene ( CYP7A1 )
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GSSG is not waste
2013;8(4):e61876
Your provider can adjust your titration speed if side effects are severe, help you find more affordable medication options if cost is an issue, work with pharmacies to resolve supply problems, or modify your treatment plan based on how you are responding
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