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Patients with pituitary adenomas also have increased DNA damage in peripheral blood lymphocytes due to the GH excess secretion ( IGF1 Promotes DNA Damage Repair of DNA DBSs IGF1 and IGF1R are necessary for nucleotide excision repair (Loesch et al., 2016)

Growth hormonereleasing peptide 6 protection of hypothalamic neurons from glutamate excitotoxicity is caspase independent and not mediated by insulinlike growth factor I

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Bellinger FP, Bellinger MT, Seale LA, Takemoto AS, Raman AV, Miki T et al